Liver failure can occur rapidly, in a matter of weeks (acute liver failure), or it can occur slowly over months and years (chronic liver failure). There are different causes for liver failure such as chronic viral infection with B and C virus, liver tumor, alcoholism, fatty liver, bile duct abnormalities (primary biliary cholangitis, primary sclerosing cholangitis, and biliary duct atresia). Hepatitis B and C are the two most common infections across the world. Luckily there is an effective vaccine for hepatitis B and cure by drugs for hepatitis C. Primary Liver Cancer develops in chronically diseased livers and sometimes develops rapidly so that no treatment is possible. If picked up on screening when the size is small, a liver transplant can cure these patients. In Liver Transplant and HPB Surgery Department we Medicity Guwahati ensures that the patient receives intense care during and after the surgery.